Preheat the oven to 400°F and spray a 9-inch pie plate with nonstick spray.

Heat a skillet over medium and add the ground beef; cook until no pink remains and you hear a steady sizzle.

Drain any fat, return the pan to medium, and stir in the taco seasoning; the aroma will bloom in about a minute.

Add the diced green chiles and salsa; stir until glossy and slightly thickened, about 2 minutes.

Spread the beef mixture evenly in the prepared pie plate and sprinkle the grated cheddar over the top.

In a medium bowl, whisk the Bisquick, milk, and eggs until smooth; it should pour like cream.

Pour the batter over the beef and cheese slowly; you’ll see it settle between pockets of filling.

Bake until the top turns golden and a toothpick in the center comes out clean, 25–30 minutes; the edges should look set and puffed.